Sulforaphane
Sulforaphane and broccoli sprouts help to prevented and remove cancer (R).
A diet rich in Brassica vegetables decreases the risk of cancer (R, R). Three to five servings per week are sufficient to decrease the risk of cancer by ∼30%–40% (R).
Subjects who consumed at least one portion of cruciferous vegetables per week had a significantly reduced risk of oral cavity, pharynx, esophageal, colorectal, breast, and kidney cancers (R).
Sulforaphane kills cancer cells, but seems to have very little effect on healthy cells (R).
Sulforaphane treatment reduce DNA damage and mutation rate when cancer-causing chemicals bind DNA (R).
Sulforaphane kills colorectal cancer cells (R), oral squamous cell carcinoma cells (R), breast cancer cells (R), cervical cancer cells, liver cancer cells, prostate cancer cells and leukemia cells (R, R).
SFN inhibits the growth of glioblastoma (R), thyroid (R), prostate (R), mammary (R), tongue (R) and lung cancer (R) in animals.
Broccoli sprouts significantly and dose-dependently inhibited bladder cancer development in rats (R) and UV-radiation-induced skin cancer development in mice (R).
Sulforaphane combats cancer by multiple mechanisms:
SOURCE:
https://www.selfhacked.com/blog/panacea-benefits-broccoli-sprouts-sulforaphane/#2_Sulforaphane_Prevents_and_Combats_Cancer
A diet rich in Brassica vegetables decreases the risk of cancer (R, R). Three to five servings per week are sufficient to decrease the risk of cancer by ∼30%–40% (R).
Subjects who consumed at least one portion of cruciferous vegetables per week had a significantly reduced risk of oral cavity, pharynx, esophageal, colorectal, breast, and kidney cancers (R).
Sulforaphane kills cancer cells, but seems to have very little effect on healthy cells (R).
Sulforaphane treatment reduce DNA damage and mutation rate when cancer-causing chemicals bind DNA (R).
Sulforaphane kills colorectal cancer cells (R), oral squamous cell carcinoma cells (R), breast cancer cells (R), cervical cancer cells, liver cancer cells, prostate cancer cells and leukemia cells (R, R).
SFN inhibits the growth of glioblastoma (R), thyroid (R), prostate (R), mammary (R), tongue (R) and lung cancer (R) in animals.
Broccoli sprouts significantly and dose-dependently inhibited bladder cancer development in rats (R) and UV-radiation-induced skin cancer development in mice (R).
Sulforaphane combats cancer by multiple mechanisms:
- SFN inhibits Phase I enzymes that can activate pro-carcinogens (R).
- SFN induces Phase II enzymes that are responsible for eliminating chemicals that damage DNA (R).
- SFN changes gene activation/deactivation (R). It causes demethylation, thereby restoring the activity of important tumor-suppressing and cell-cycle controlling genes (R).
- Sulforaphane induces cancer cell death (R).
- Sulforaphane inhibits the NF-κB pathway, thus reducing inflammation(R).
- Sulforaphane induces cell cycle arrest (R) and thereby inhibits cancer cell proliferation.
SOURCE:
https://www.selfhacked.com/blog/panacea-benefits-broccoli-sprouts-sulforaphane/#2_Sulforaphane_Prevents_and_Combats_Cancer
In high doses, sulforaphane is a pro-oxidant, and can help increase oxidative stress against tumor cells. R
Sulforaphane induces cell arrest and apoptosis in many types of cancer cells. R R
It inhibits the growth of benign tumors turning into malignant tumors. R
Sulforaphane is useful in prostate (via HDAC inhibition) and colorectal cancers (increasing TGF-B receptors and inducing apoptosis). R R R
SOURCE:
https://mybiohack.com/blog/the-15-benefits-of-sulforaphane-glucoraphanin-broccoli-sprouts-nrf2-cancer-longevity-aging-cooking
Sulforaphane induces cell arrest and apoptosis in many types of cancer cells. R R
It inhibits the growth of benign tumors turning into malignant tumors. R
Sulforaphane is useful in prostate (via HDAC inhibition) and colorectal cancers (increasing TGF-B receptors and inducing apoptosis). R R R
SOURCE:
https://mybiohack.com/blog/the-15-benefits-of-sulforaphane-glucoraphanin-broccoli-sprouts-nrf2-cancer-longevity-aging-cooking
Surprising Discovery Reveals How Broccoli Fights Cancer
https://articles.mercola.com/sites/articles/archive/2017/04/03/how-sulforaphane-fights-cancer.aspx
https://articles.mercola.com/sites/articles/archive/2017/04/03/how-sulforaphane-fights-cancer.aspx
Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts.https://www.ncbi.nlm.nih.gov/pubmed/23902242/
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